NAD+

Formulation: 2.6 mL pre-filled pen

Clicks per Pen: 240

Total Amount: 1000 mg Nicotinamide Adenine Dinucleotide (NAD+)

Supplied with: 6 sterile needles (additional needles available separately)

Description

The NAD+ Pen contains Nicotinamide Adenine Dinucleotide (NAD+), an essential coenzyme naturally present in every living cell. NAD+ plays a central role in cellular energy production, mitochondrial function, DNA repair, and healthy aging.

Structurally, NAD+ consists of two nucleotides joined by phosphate groups—one containing adenine and the other nicotinamide. It continuously cycles between its oxidized (NAD+) and reduced (NADH) forms, allowing it to participate in hundreds of metabolic reactions responsible for converting nutrients into usable cellular energy.

Mechanism of Action

NAD+ functions as a critical cofactor for several enzyme systems that regulate energy production, cellular repair, and metabolic health, including:

• Sirtuins (SIRT1-SIRT7): Support DNA repair, mitochondrial biogenesis, epigenetic regulation, inflammation control, and longevity pathways.
• PARPs (Poly ADP-Ribose Polymerases): Detect and repair DNA damage while maintaining genomic stability.
• CD38 and CD157: Regulate calcium signaling, immune function, and NAD+ metabolism.

Supplementation helps replenish declining NAD+ levels associated with aging and physiological stress. Elevated NAD+ availability supports:

• Enhanced mitochondrial ATP production
• Improved oxidative phosphorylation and energy metabolism
• Activation of cellular repair pathways
• Reduced oxidative stress
• Improved metabolic flexibility and insulin sensitivity
• Greater resilience against age-related cellular dysfunction

Indications & Usage

The NAD+ Pen is formulated to support healthy cellular function and metabolic performance. It may be used to assist with:

• Restoring healthy intracellular NAD+ levels
• Supporting cellular energy production
• Promoting mitochondrial efficiency and metabolic function
• Enhancing endurance, vitality, and recovery
• Supporting healthy aging and cellular repair mechanisms
• Improving metabolic resilience during periods of increased physical or mental demand

Contraindications & Warnings

Do not use if you have:

• Known hypersensitivity to NAD+ or any formulation ingredient
• Active malignancy (due to theoretical concerns regarding enhanced cellular metabolism)
• Severe liver or kidney disease
• Pregnancy or breastfeeding
• Are under 18 years of age

Warnings

• Use only under the supervision of a qualified healthcare professional.
• Routine monitoring of liver function, glucose metabolism, and other clinical markers may be appropriate during extended use.
• This product should not replace a healthy lifestyle or established medical treatment for metabolic or age-related conditions.
• Higher doses may occasionally cause temporary flushing, gastrointestinal discomfort, or fluctuations in energy levels.
• Discontinue use immediately and seek medical attention if severe abdominal pain, allergic reactions, or unexpected neurological symptoms occur.

Dosage & Administration

For subcutaneous injection only.

Standard Maintenance Dose

• 50 mg per injection
• 12 clicks

Performance Dose

• 75 mg: approximately 18 clicks
• 100 mg: 24 clicks

Frequency

Loading Phase (Weeks 1-2)

• 50 mg daily or 5-7 injections per week

Maintenance

• 2-3 injections weekly or every second day

Recommended Timing

• Morning or before activity to support energy and performance
• Evening when focusing on recovery and cellular restoration

Suggested Cycle

• 4-12 weeks of continuous use, followed by approximately 4 weeks off before beginning another cycle.

Administration Instructions

1. Wash hands thoroughly and prepare a clean workspace.
2. Attach a new sterile needle.
3. Dial the required number of clicks.
4. Clean the injection site (abdomen or thigh) with an alcohol swab.
5. Insert the needle at a 45-90° angle and inject slowly.
6. Remove the needle and dispose of it safely.
7. Replace the pen cap after each use.
8. Rotate injection sites regularly to minimize irritation.
9. Inspect the solution before every injection. Do not use if the solution is cloudy, discoloured, or contains visible particles.

Possible Side Effects

NAD+ is generally well tolerated when used appropriately. Mild and temporary side effects may include:

• Injection-site redness, itching, or mild discomfort
• Temporary headache, flushing, or light-headedness
• Mild nausea, bloating, or gastrointestinal discomfort
• Temporary fatigue or changes in energy levels during early use
• Rare hypersensitivity reactions

Discontinue use and seek medical advice if severe or persistent symptoms develop, including severe headache, abdominal pain, breathing difficulty, or signs of an allergic reaction.

Storage & Handling

• Store refrigerated or in a cool, dry place (maximum 25-30°C).
• Never freeze.
• Keep the pen tightly capped and protected from heat and direct sunlight.
• Continue storing under the same conditions after first use.
• Keep out of reach of children.
• Do not use after the expiry date or if the solution appears abnormal.

Powered by Precision MSSPT

Every Peptide Pen is manufactured using Precision MSSPT (Multi-Stage Stabilization and Preservation Technology), an advanced stabilization platform developed to maintain peptide integrity in demanding environments.

Through proprietary buffering systems, antioxidants, and specialized stabilizing agents, MSSPT helps protect the formulation against heat, light, oxygen, moisture, pH fluctuations, and oxidative degradation. This technology provides exceptional molecular stability and dosing consistency—even in challenging climates such as South Africa and the UAE.

With no mixing or reconstitution required, every Peptide Pen delivers convenient, ready-to-use administration with reliable precision from the first dose to the last.

IMPORTANT NOTICE

This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the FDA, SAHPRA, or any other regulatory authority.

Always consult a qualified healthcare professional before use, particularly if you are pregnant, breastfeeding, under 18 years of age, taking prescription medication, or managing an existing medical condition.