NMN

Formulation: 2.6 mL pre-filled pen

Clicks per Pen: 240

Total Content: 1,500 mg Nicotinamide Mononucleotide (NMN)

Supplied with: 6 sterile needles (additional needles available separately)

Description

The NMN Pen contains Nicotinamide Mononucleotide (NMN), a naturally occurring nucleotide and direct precursor to Nicotinamide Adenine Dinucleotide (NAD⁺)—an essential coenzyme involved in cellular energy production, DNA repair, and healthy aging.

NMN is synthesized from vitamin B3 (niacin), nicotinamide, nicotinamide riboside, and ribose. Its molecular formula is C₁₁H₁₅N₂O₈P, consisting of a nicotinamide group attached to a phosphorylated ribose molecule. By increasing intracellular NAD⁺ levels, NMN helps support mitochondrial health, metabolic function, and overall cellular performance.

Mechanism of Action

Following administration, NMN is readily absorbed by cells through specialized transport mechanisms, including the Slc12a8 transporter, and is converted into NAD⁺ via the cellular salvage pathway by NMN adenylyltransferase (NMNAT1-3) enzymes.

Elevated NAD⁺ levels support several important biological processes by activating key enzyme systems, including:

• Sirtuins (SIRT1-SIRT7): Regulate gene expression, mitochondrial biogenesis, inflammation control, DNA repair, and healthy aging.
• PARPs (Poly ADP-Ribose Polymerases): Assist with DNA repair and maintenance of genomic stability.
• CD38/CD157: Support calcium signalling, immune regulation, and NAD⁺ metabolism.

Together, these mechanisms help:

• Enhance mitochondrial energy (ATP) production
• Improve metabolic efficiency and flexibility
• Support insulin sensitivity
• Reduce oxidative stress
• Promote cellular repair and resilience
• Support healthy aging and cognitive performance

Indications & Usage

NMN is formulated to support cellular energy production, mitochondrial function, and age-related physiological health. It may assist with:

• Restoring and maintaining healthy NAD⁺ levels
• Supporting mitochondrial performance and ATP production
• Promoting metabolic efficiency and insulin sensitivity
• Assisting recovery from age-related declines in energy and endurance
• Supporting cognitive function and healthy aging
• Enhancing overall vitality and physical performance

Contraindications & Warnings

Do not use if you have:

• Known hypersensitivity to NMN or any ingredient in the formulation
• Active malignancy or cancer (due to theoretical concerns regarding enhanced cellular metabolism)
• Severe liver or kidney impairment
• Pregnancy or breastfeeding
• Are under 18 years of age

Warnings

• Use only under the supervision of a qualified healthcare professional.
• Periodic monitoring of liver function, glucose metabolism, and relevant clinical markers is recommended.
• This product should not replace appropriate medical treatment or healthy lifestyle practices.
• Higher doses may occasionally cause temporary flushing or mild gastrointestinal discomfort.
• Stop use immediately and seek medical attention if severe abdominal pain, allergic reactions, or unexpected neurological symptoms occur.

Dosage & Administration

For subcutaneous injection only.

Daily Wellness / Longevity

• 3-4 clicks each morning
• Approximately 18.75-25 mg NMN

Therapeutic / Mitochondrial Support

• 8-12 clicks daily
• Approximately 50-75 mg NMN
• Recommended 5 days per week

High-Performance / Anti-Aging Protocol

• 20 clicks per injection
• Approximately 125 mg NMN
• Administer three times weekly
• Typical cycle: 4-6 weeks

Frequency

• Daily for wellness and mitochondrial support
• Three times weekly for higher-intensity protocols

Timing

Morning administration is generally preferred to support daytime energy production and NAD⁺ metabolism, or as directed by your healthcare professional.

Administration Instructions

1. Wash your hands thoroughly and prepare a clean working area.
2. Attach a new sterile needle.
3. Dial the prescribed number of clicks.
4. Clean the injection site (abdomen or upper thigh) using an alcohol swab.
5. Insert the needle at a 45-90° angle and inject slowly.
6. Remove the needle and dispose of it safely.
7. Replace the pen cap after use.
8. Rotate injection sites to minimise irritation.
9. Always inspect the solution before use. Do not inject if the solution is cloudy, discoloured, or contains visible particles.

Side Effects

NMN has demonstrated a favourable safety profile in current research and is generally well tolerated. Reported adverse effects are uncommon and typically mild.

Possible side effects include:

• Mild redness, itching, or discomfort at the injection site
• Temporary headache or light-headedness
• Mild flushing
• Occasional nausea or bloating
• Temporary fatigue or changes in energy during the initial stages of use

If severe or persistent symptoms occur—including significant abdominal pain, allergic reactions, or other unexpected effects—stop use and consult your healthcare provider immediately.

Storage & Handling

• Store refrigerated where possible. Do not freeze.
• Alternatively, store in a cool, dry location below 25-30°C (77-86°F).
• Keep the pen protected from heat, moisture, and direct sunlight.
• Always replace the cap after use.
• Maintain the same storage conditions after first use.
• Keep out of reach of children.
• Do not use if the product has expired or if the solution appears abnormal.

Powered by Precision MSSPT

The NMN Pen is manufactured using Precision MSSPT (Multi-Stage Stabilization and Preservation Technology), an advanced formulation system developed to maximize peptide and compound stability under challenging environmental conditions.

Each pen incorporates specialized buffering systems, antioxidants, and proprietary stabilizing agents that help protect against degradation caused by heat, oxygen, moisture, oxidation, and light. Designed specifically for demanding climates such as South Africa and the UAE, MSSPT helps maintain product integrity, potency, and dosing consistency throughout the life of the pen.

The result is a ready-to-use formulation requiring no mixing, delivering reliable performance and precision from the first dose to the last.

IMPORTANT NOTICE

This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the FDA, SAHPRA, or any other regulatory authority. Always consult a qualified healthcare professional before using this product, particularly if you are pregnant, breastfeeding, under 18 years of age, or have an existing medical condition.